Sur le Web, ces 30 derniers jours

mardi 18 septembre 2018

  • Mepsevii vestronidase alfa
  • Duzallo allopurinol / lesinurad
  • Nerlynx neratinib
  • Yescarta axicabtagene ciloleucel
  • Cablivi caplacizumab
  • Ulipristal Acetate Gedeon Richter
  • Intelligence plurielle et collective : salon
    Découvre tes 4 intelligences ! Le samedi 20 octobre 2018 à partir de 12H00 à Tour & Taxis Entrée libre Cette année, le salon MYND en sera à sa cinquième édition et il y aura plein de nouveautés. En plus de rencontrer des associations bruxelloises qui développeront tes différentes intelligences, tu (...)

  • PROLIA (ostéoporose post ménopausique)
    Le service médical rendu par PROLIA reste important dans le traitement de l’ostéoporose post-ménopausique en deuxième intention en relais des bisphosphonates uniquement chez les patientes à risque élevé de fracture. Les patientes à risque élevé de fracture sont définies comme : - patientes ayant fait une (...)

  • KYPROLIS (carfilzomib), antinéoplasique
    KYPROLIS a l’AMM en association à la dexaméthasone seule dans le traitement du myélome multiple chez les adultes qui ont reçu au moins un traitement antérieur. Sa posologie en bithérapie est différente de celle de la trithérapie. La supériorité de la bithérapie associant KYPROLIS à la dexaméthasone par (...)

  • Changement de la dénomination de CREON 12 000 U, gélule gastro-résistante en CREON 10 000 U, gélule gastro-résistante - Lettre aux professionnels de santé
    La dénomination de la spécialité CREON 12 000 U est modifiée en CREON 10 000 U, afin de mieux refléter l’activité lipolytique réelle de la pancréatine contenue dans les gélules. Il n’y a aucune différence entre CREON 12 000 U et 10 000 U : la composition du médicament demeure inchangée ; ce changement de (...)

  • YERVOY (ipilimumab), anticorps monoclonal
    YERVOY en monothérapie a l’AMM dans le traitement de traitement des patients adolescents de 12 ans et plus atteints de mélanome avancé (non résécable ou métastatique). Son intérêt clinique est insuffisant chez les adolescents (âgés de 12 à 17 ans inclus), naïfs de traitement ou prétraités, compte tenu (...)

  • CEFTRIAXONE GERDA
    Service Médical Rendu (SMR). Important. Le service médical rendu par CEFTRIAXONE GERDA 1g, poudre pour solution injectable et CEFTRIAXONE GERDA 2g, poudre pour solution pour perfusion est important dans les indications de l’AMM. Amélioration du service médical rendu (ASMR). V (absence). Ces (...)

  • Highlights for September 18, 2018
  • Prospects for a Deep Learning Health Care System
    In this Viewpoint, David Naylor reviews factors driving the adoption of deep learning and artificial intelligence in health care, including the digitization of health data and efficiencies in processing those data sets to automate routine clinical tasks and accelerate research and technology (...)

  • The Potential of Deep Learning Technology to Transform Health Care
    In this Viewpoint, Geoffrey Hinton of Google’s Brain Team discusses the basics of neural networks: their underlying data structures, how they can be trained and combined to process complex health data sets, and future prospects for harnessing their unsupervised learning to clinical (...)

  • Informatics, Data Science, and Artificial Intelligence
    This Viewpoint discusses how advances in data science and informatics are driving a transformation of biomedical research and clinical practice toward models where data mining and artificial intelligence will underlie development of precision (...)

  • Moments of Silence in the Intensive Care Unit
    In this narrative medicine essay, an intensivist tells how he and his colleagues joined in a moment of silence to honor the ICU death of a man under their care with a do-not-resuscitate order.

  • Clinical Implications and Challenges of Artificial Intelligence and Deep Learning
    Artificial intelligence (AI) and deep learning are entering the mainstream of clinical medicine. For example, in December 2016, Gulshan et al reported development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs. An accompanying (...)

  • Symptoms of Burnout Among Physicians
    A patient complains of intermittent wheezing. He cannot characterize the wheezing further with regard to timing, precipitating events, or how it affects his health. A physician makes a diagnosis of asthma without further evaluation, gives the patient several recommendations regarding lifestyle (...)

  • Weight Management in Adults With Obesity
    In this issue of JAMA, the US Preventive Services Task Force (USPSTF) presents its 2018 recommendation statement and an accompanying evidence review on weight loss interventions to prevent obesity-related morbidity and mortality in adults. In this update of the 2012 USPSTF recommendation, the (...)

  • Association of Clinical Specialty With Symptoms of Burnout and Regret Among US Resident Physicians
    This survey study investigates risk factors for symptoms of burnout and career choice regret among US physicians during their second year of residency.

  • Prevalence of Burnout Among Physicians
    This systematic review assesses how burnout among practicing physicians has been defined in the published medical literature and estimates its prevalence by definitions, assessment methods, and study quality.

  • Accuracy of [ 18 F]flortaucipir PET for Alzheimer Disease vs Other Neurodegenerative Disorders
    This diagnostic accuracy study characterizes the ability of [18F]flortaucipir to discriminate Alzheimer from non-Alzheimer neurodegenerative disorders among patients at dementia clinics and research centers.

  • USPSTF Recommendation: Behavioral Interventions to Prevent Adult Obesity-Related Outcomes
    This 2018 Recommendation Statement from the US Preventive Services Task Force recommends that clinicians offer or refer adults with a body mass index of 30 or higher to intensive, multicomponent behavioral interventions (B recommendation).

  • USPSTF Evidence Report: Behavioral Interventions to Prevent Adult Obesity-Related Outcomes
    This systematic review to support the 2018 US Preventive Services Task Force Recommendation Statement on interventions to prevent obesity-related morbidity and mortality summarizes published evidence on the benefits and harms of behavioral and pharmacotherapy weight loss and weight loss (...)

  • On Deep Learning for Medical Image Analysis
    This JAMA Guide to Statistics and Methods explains the basic concepts underlying convolutional neural networks (CNNs), a type of machine learning being used to automate the reading of medical images.

  • Association Between Maintaining Certification in General Surgery and Loss-of-License Actions
    This study uses American Board of Surgery data to assess the association between maintainence of certification in general surgery and loss-of-license actions after expiration of the initial 10-year certification among general (...)

  • Scholarship Support for Veterans Enrolling in MD, JD, and MBA Programs
    This study compares Veterans Administration (VA) scholarship support for veterans enrolling in degree-granting medical schools vs law or business programs at the same institutions.

  • A Day in the Life: Caring for Transgender Patients in New York City
    This Medical News article profiles Joshua D. Safer, MD, who leads Mount Sinai’s Center for Transgender Medicine and Surgery.

  • Are Bacteria Transplants the Future of Eczema Therapy?
    This Medical News article discusses early clinical trials of beneficial bacteria therapy for eczema, or atopic dermatitis.

  • Brain Stimulation Approved for Obsessive-Compulsive Disorder
    The FDA has expanded the approved indications for transcranial magnetic stimulation (TMS) to include obsessive-compulsive disorder (OCD). In 2008, TMS was approved to treat major depression and in 2013 got the nod for pain from certain migraine (...)

  • Generic Form of EpiPen Approved
    Aiming to spur competition, lower prices, and ward off drug shortages, the FDA approved the first generic epinephrine autoinjector to treat life-threatening allergic reactions. The approval came 2 years after public outcries concerning steep price hikes for the brand name product, EpiPen, (...)

  • Vaginal Ring Contraceptive Remains Effective for 1 Year
    The first vaginal ring contraceptive that women can use for a full year has received FDA approval. In comparison, a contraceptive ring currently marketed in the United States has to be replaced monthly.

  • Enabling School Success to Improve Community Health
    From an innovative play space designed to teach children about concepts of engineering and mathematics to an outdoor teaching kitchen to help students learn about nutrition and to new school health services for vulnerable teens, several (...)

  • Armadillos Bring Risk of Leprosy
    Armadillos can serve as an environmental reservoir for Mycobacterium leprae, the bacterial agent that causes leprosy, and hunting, handling, or eating armadillo meat can increase the risk of infection, report an international team of researchers in PLoS Neglected Tropical (...)

  • Cardiovascular Disease in India
    Ischemic heart disease deaths are rising in India, particularly in rural areas and among young adults, while deaths from stroke have dropped in most parts of the country, according to a study in The Lancet Global Health.

  • Early Initiation of Breastfeeding
    Globally, only 2 out of 5 newborns began breastfeeding within an hour of birth in 2017, leaving an estimated 78 million newborns to wait over 1 hour to be put to the breast, according to a new report from the United Nations Children’s Fund (UNICEF) and the World Health Organization (...)

  • Premedication for Neonates and Nonemergency Intubation
    To the Editor Dr Durrmeyer and colleagues investigated 173 neonates requiring nonemergent intubation in a multicenter, double-blind clinical trial, randomly assigning infants to receive atropine-propofol or atropine-atracurium-sufentanil before nasotracheal intubation. The authors reported that (...)

  • Premedication for Neonates and Nonemergency Intubation—Reply
    In Reply Drs Fideler and Grasshoff raise 2 concerns regarding our trial comparing 2 premedication regimens for neonates requiring nonemergency intubation in the neonatal intensive care unit (NICU). Concerning the potential neurotoxicity of anesthetics and analgesics on the developing human (...)

  • Safety of Topical Calcineurin Inhibitors for Hailey-Hailey Disease
    To the Editor Dr Haley and colleagues described a patient with Hailey-Hailey disease (HHD) in a JAMA Clinical Challenge article. The authors stated that long-term topical calcineurin inhibitors (TCIs) such as tacrolimus or pimecrolimus could be applied to control HHD because they lacked the (...)

  • Safety of Topical Calcineurin Inhibitors for Hailey-Hailey Disease—Reply
    In Reply Mr Han raises an important point regarding the use of TCIs, which are labeled for use in atopic dermatitis, to treat HHD. The FDA issued a black box warning of a possible association between TCI use and the development of cancer (lymphoma and skin) based on case reports and animal (...)

  • Treatment of Chronic Hepatitis B Infection
    To the Editor Dr Tang and colleagues summarized the current clinical evidence on the management of chronic hepatitis B virus (HBV) infection. I have some concerns about the review. First, it is not adequate to designate HBV e antigen (HBeAg) as HBV envelope antigen. HBeAg is not a structural (...)

  • Treatment of Chronic Hepatitis B Infection—Reply
    In Reply The e in HBeAg has been referred to as an abbreviation for “envelope” in several recent studies. Magnius and Espmark first described a new antigenic specificity in individuals positive for Australia antigen (now known as HBsAg) and proposed the designation of e for this new specificity. (...)

  • Incorrect Expansion of a Term and Other Clarifications
    In the Review entitled “Chronic Hepatitis B Infection: A Review” published in the May 1, 2018, issue of JAMA, the term “hepatitis B envelope antigen” should have been “hepatitis B e antigen” in several places throughout the article. In Figure 1, the hepatitis e antigen was removed from the depiction (...)

  • Spring Downsizing
    The lilac buds  are plumper now,unharmed  by April snows.A colony of ladybugs  feeds on honeyyou dabbed  on our antique window.Our last April here,  we inventorywhat we’ll keep,  what must go.

  • Proprietaries, Pianos and Probity
    A correspondent, in calling attention to one of a series of resolutions we quoted last week, comments as follows: “Had this resolution been passed by the American Medical Association and been endorsed and published by The Journal, I am inclined to think that frenzied protests would have arisen (...)

  • Behavioral Interventions for Weight Loss
    This JAMA Patient Page describes the US Preventive Services Task Force’s recent recommendations on behavioral interventions for weight loss to prevent obesity-related problems in adults.

  • JAMA

lundi 17 septembre 2018

  • APALUTAMIDE 60 mg, comprimé pelliculé
    APALUTAMIDE est indiqué dans le traitement des hommes atteints d’un cancer de la prostate résistant à la castration non métastatique (nmCRPC) avec un temps de doublement du taux de PSA inférieur ou égal à 10 mois...

  • Le Choix - Citoyens pour une mort choisie
    L'association a pour objet: Le soutien et la promotion de textes législatifs dont le contenu sera de permettre aux personnes identifiées par la loi de choisir le mode et le moment de leur fin de vie. Le partage d’informations et de renseignements ayant trait à la fin de vie. L’organisation (...)

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